Gene and Drug Landing Page Aggregator

Gene and Drug Landing Page Aggregator (GDLPA) has links to 53 gene, 18 variant and 19 drug repositories that provide direct links to gene and drug landing pages. You can search by gene or drug name and then choose the sites that contain knowledge about your gene or drug of interest. Resources supported by the NIH Common Fund are listed first and have the CFDE logo at their top right corner.

Gene Examples: ACE2, ULK4, DPH7, KL
Variant Examples: chr1:g.115879821G>C, rs28897756

Gene-gene interactions (GGIs) from literature 

Gene-gene interactions (GGIs) from mRNA co-expression 

MaayanLab
ARCHS4
ARCHS4 site image

ARCHS4 provides access to gene counts from HiSeq 2000, HiSeq 2500 and NextSeq 500 platforms for human and mouse experiments from GEO and SRA.

GWAS image
GWAS site image

The GWAS Catalog provides a consistent, searchable, visualisable and freely available database of SNP-trait associations, which can be easily integrated with other resources.

MaayanLab
Enrichr
Enrichr site image

Enrichr is an enrichment analysis tool that provides various types of visualization summaries of collective functions of gene sets.

MaayanLab
Harmonizome
Harmonizome screenshot

The Harmonizome is a collection of knowledge about genes and proteins from 114 datasets created by processing 66 online resources to facilitate discovery via data integration.

CFDE Search Portal
CFDE Search Portal site image

The CFDE Search Portal is a hub for searching the CFDE data across all programs. The main page of the portal (shown below) is meant for high-level decision-making, whereas the repository (or “data browser”) allows users such as clinical researchers, bioinformatics power users, and NIH program officers to search for CFDE data.

GeneMANIA site logo
GeneMANIA site image

GeneMANIA builds subnetworks around an input gene using functional association data.

Reactome image
Reactome site image

Reactome is a free, open-source, curated and peer-reviewed pathway database that provides intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge.

PDBe image
PDBe site image

PDBe Knowledge Base is a community-driven resource managed by the PDBe team, collating functional annotations and predictions for structure data in the PDB archive.

MaayanLab
CFDE Gene Partnership Appyter
Appyter screenshot

CFDE Gene Partnership uses FAIR APIs from different DCCs to find and present gene-centric knowledge.

COSMIC image
COSMIC site image

COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer.

GlyGen image
GlyGen site image

GlyGen provides computational and informatics resources and tools for glycosciences research using information from many data sources.

IDG
LDP 3.0
IDG Reactome Portal site image

IDG Reactome Portal provides biologist-friendly way to visualize proteins, complexes, and reactions in high-quality Reactome pathways.

STRING image
STRING site image

STRING is a database of known and predicted protein-protein interactions and a functional enrichment tool covering more than 5000 genomes.

AlphaFold logo
AlphaFold site image

AlphaFold DB provides open access to protein structure predictions for the human proteome and 20 other key organisms to accelerate scientific research.

MARRVEL image
MARRVEL site image

MARRVEL enables users to search multiple public variant databases simultaneously and provides a unified interface to facilitate the search process.

LINCS image
SigCom LINCS
SigCom LINCS site image

SigCom LINCS data portal serves LINCS datasets and signatures. It provides a signature similarity search to query for mimicker or reverser signatures.

BioGPS image
BioGPS site image

BioGPS is a free extensible and customizable gene annotation portal, a complete resource for learning about gene and protein function.

GTEx logo
GTEx site screenshot

The Genotype-Tissue Expression (GTEx) Portal provides open access to data including gene expression, QTLs, and histology static.

MetGENE logo
MetGENE site screenshot

The objective of MetGENE is to identify the reactions catalyzed by the given gene(s) RPE and the related metabolites.

IDG
Pharos
Pharos screenshot

The Pharos interface provides facile access to most data types collected by the Knowledge Management Center for the IDG program.

MaayanLab
PrismEXP logo
PrismEXP Appyter site image

Automated Vector Quantization of Massive Co-expression RNA-seq Data Improves Gene Function Prediction (PrismEXP) is a new statistical approach for accurate gene function prediction.

MaayanLab
Gene Centric GEO Reverse Search Appyter
Appyter screenshot

Gene Centric GEO Reverse Search Appyter enables users to query for a gene in a species of interest; it returns an interactive volcano plot of signatures in which the gene is up- or down-regulated.

HGNC image
HGNC site image

The HGNC database is a curated online repository of approved gene nomenclature, gene groups and associated resources including links to genomic, proteomic and phenotypic information.

Human Genome Browser image
Human Genome Browser site image

The Human Genome Browser includes a broad collection of vertebrate and model organism assemblies and annotations, along with a large suite of tools for viewing, analyzing and downloading data.

KEGG image
KEGG site image

KEGG is a database resource for understanding high-level functions and utilities of the biological system from molecular-level information.

MGI image
MGI site image

MGI is the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data to facilitate the study of human health and disease.

MaayanLab
RGCSRS Appyter
RGCSRS Appyter site image

The RGCSRS Appyter provides visualizations of the RNA-seq signatures induced by CRISPR knockouts and chemical perturbagens. Signatures are computed from transformed data profiles from the LINCS L1000 data.

Bgee image
Bgee site image

Bgee is a database for retrieval and comparison of gene expression patterns across multiple animal species.

Human Protein Atlas site logo
Human Protein Atlas site image

The Human Protein Atlas aims to map all human proteins in cells, tissues and organs using the integration of various omics technologies.

NCBI image
NCBI site image

The NCBI Gene Database page provides information about nomenclature, RefSeqs, maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources.

OMIM image
OMIM site image

OMIM is a comprehensive, authoritative compendium of human genes and genetic phenotypes that is freely available and updated daily.

Uniprot image
UniProt site image

The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.

KOMP image
IMPC site image

The Knockout Mouse Programme - International Mouse Phenotyping Consortium (KOMP-IMPC) has information about the functions of protein-coding genes in the mouse genome.

Metabolomics image
Metabolomics site image

The Metabolomics Workbench serves as a repository for metabolomics data and metadata and provides analysis tools.

Monarch Initiative image
Monarch Initiative site image

The Monarch Initiative is an integrative data and analytic platform connecting phenotypes to genotypes across species, bridging basic and applied research with semantics-based analysis.

WikiPathways logo
WikiPathways site image

WikiPathways was established to facilitate the contribution and maintenance of pathway information by the biology community.

ENCODE image
ENCODE site image

The ENCODE Consortium not only produces high-quality data, but also analyzes the data in an integrative fashion.

Ensembl image
Ensembl site image

Ensembl is a genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation.

Gene Ontology image
Gene Ontology site image

The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes.

PDB image
PDB site image

PDB has information about the 3D shapes of proteins, nucleic acids, and complex assemblies that contribute to understanding everything from protein synthesis to health and disease.

PubMed image
PubMed site image

PubMed comprises more than 33 million citations for biomedical literature from MEDLINE, life science journals, and online books.

Wikipedia image
Wikipedia site image

Wikipedia is a free content, multilingual online encyclopedia written and maintained by a community of volunteers through a model of open collaboration, using a wiki-based editing system